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Updated on January 17, 2024

CBD for Endometriosis

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Key takeaways

  • People with endometriosis experience pain that can be hard to manage.
  • Statistics show that about 10% of women and girls of reproductive age are affected by endometriosis.
  • CBD works for endometriosis in two ways; pain relief and hormonal balance.
  • CBD is useful for relieving endometriosis-induced pain

What is endometriosis?

Endometriosis is a medical condition that affects women and girls of reproductive age. Statistics show that about 10% of women and girls of reproductive age are affected by endometriosis. Normally, the tissue that lines the inside of the uterus is called the endometrium. In endometriosis, this tissue starts growing outside the uterus, such as on the ovaries, fallopian tubes, or other pelvic organs.

During the menstrual cycle, this misplaced tissue can cause pain, inflammation, and the formation of scar tissue. It can also lead to fertility issues in some cases. Endometriosis is a chronic condition, and managing its symptoms often involves medical treatments and, in some cases, surgery.

What are the causes of endometriosis?

The exact cause of endometriosis is not fully understood, but several factors may contribute to its development. Here are some potential causes or factors associated with endometriosis:

  1. Retrograde Menstruation: One common theory suggests that during menstruation, some menstrual blood containing endometrial cells flows backward into the pelvic cavity instead of exiting the body. These displaced cells can then attach to pelvic organs and grow, leading to endometriosis.
  2. Genetic Factors: There is evidence to suggest a genetic predisposition to endometriosis. If close family members, such as a mother or sister, have endometriosis, the risk of developing the condition may be higher.
  3. Immune System Dysfunction: Issues with the immune system may play a role in allowing endometrial tissue to grow outside the uterus. A compromised immune response may fail to eliminate misplaced cells effectively.
  4. Hormonal Influence: Hormones, particularly estrogen, play a crucial role in the menstrual cycle and may influence the development of endometriosis. The condition often improves after menopause when estrogen levels decline.
  5. Surgical Scars: Previous surgeries, such as a cesarean section or hysterectomy, can lead to the implantation of endometrial tissue in the surgical scars.
  6. Environmental Factors: Exposure to certain environmental factors, such as toxins or pollutants, may contribute to the development of endometriosis. However, more research is needed to understand the specific environmental influences.
  7. Immune System Disorders: Conditions that affect the immune system, such as autoimmune disorders, may be associated with an increased risk of endometriosis.

What are the symptoms of endometriosis?

Endometriosis can cause various symptoms, and their severity can vary. Common symptoms of endometriosis include:

  1. Pelvic Pain: Persistent pelvic pain is a hallmark symptom of endometriosis. The pain may be constant or cyclical, intensifying before and during menstruation.
  2. Painful Periods (Dysmenorrhea): Women with endometriosis often experience more intense menstrual cramps than usual. The pain may extend beyond the pelvic area.
  3. Painful Intercourse (Dyspareunia): Sexual intercourse can be painful for individuals with endometriosis, particularly during deep penetration.
  4. Painful Bowel Movements or Urination: Endometrial tissue outside the uterus can affect the bowel and bladder, leading to pain during bowel movements or urination, especially during menstruation.
  5. Excessive Bleeding: Some women with endometriosis may experience heavy menstrual bleeding or irregular periods.
  6. Fatigue: Chronic pain and other symptoms of endometriosis can contribute to fatigue and a general feeling of tiredness.
  7. Gastrointestinal Issues: Endometrial tissue in the abdomen may cause gastrointestinal symptoms such as bloating, constipation, or diarrhea, particularly during menstruation.
  8. Lower Back Pain: Some individuals with endometriosis experience lower back pain that may be associated with pelvic discomfort.
  9. Painful Ovulation: Pain or discomfort during ovulation is another symptom that some women with endometriosis may experience.

How does CBD work for endometriosis?

CBD can assist people suffering with endometriosis in two ways which are discussed below;

  1. Pain relief

CBD has a great potential for pain relief. Researchers have reported the analgesic roles of CBD in reducing pain associated with inflammation, menstrual cramps and arthritis. This pain-relieving property can be very useful to people who are dealing with endometriosis. It can serve as a key ingredient for pain relief.

  1. Hormonal balance

CBD may play a role in helping to balance hormones by interacting with the endocannabinoid system (ECS). The ECS is a complex system in the body that helps regulate various processes, including hormones. By affecting this system, CBD may indirectly impact hormonal levels.

Chronic stress can disrupt hormones like cortisol and contribute to issues such as adrenal fatigue. CBD has been studied for its potential to reduce stress and anxiety, potentially contributing to maintaining hormonal balance. The hypothalamus and pituitary gland are important parts of the brain involved in regulating hormones. Some studies suggest that CBD may influence these brain regions, potentially affecting hormone secretion.

CBD is also known for its anti-inflammatory properties. Since inflammation can contribute to hormonal imbalances, reducing inflammation with CBD may indirectly support hormonal balance.

What are the best CBD products for endometriosis?

Full spectrum CBD oils, cream, tincture and salves may be an excellent choice for people suffering with endometriosis. These types of products will allow excellent interaction between the ECS and their receptors. It is also important to ensure the products come from a reputable source as contaminated products can increase the pain associated with endometriosis. This is why Nesas hemp is fully invested in full spectrum CBDa organic hemp oils. Our products come with zero pesticides, and additives.

How to dose CBD for endometriosis?

Dosing CBD for endometriosis requires several trial and error processes. Since the level of interaction between ECS receptors and CBD may differ from person to person, it is important to start small and go slow. You can start with a low as 20mg per day and increase until you find your CBD sweet spot. CBD sweet spot is that dosage at which your body experiences the best CBD effects.

Frequently asked questions

Are there clinical trials on CBD for endometriosis?

Yes, there are a few clinical trials looking at the possible role of CBD for endometriosis pain.

Can CBD be used to manage endometriosis-related inflammation?

Yes, CBD's anti-inflammatory properties may help in managing inflammation associated with endometriosis. Research suggests it could modulate the immune response and reduce inflammation, contributing to symptom relief.

What dosage of CBD is recommended for endometriosis?

CBD dosage can vary based on factors such as body weight, individual response, and the severity of symptoms. It's advisable to start with as low as 20mg and adjust accordingly.

Can CBD be used for endometriosis-related sleep disturbances?

Yes, CBD's potential calming effects may help manage sleep disturbances related to endometriosis.

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Farooqi, T.; Bhuyan, D.J.; Low, M.; Sinclair, J.; Leonardi, M.; Armour, M. Cannabis and Endometriosis: The Roles of the Gut Microbiota and the Endocannabinoid System. J. Clin. Med. 202312, 7071.

Genovese T, Cordaro M, Siracusa R, Impellizzeri D, Caudullo S, Raffone E, Macrí F, Interdonato L, Gugliandolo E, Interlandi C, Crupi R, D'Amico R, Fusco R, Cuzzocrea S, Di Paola R. Molecular and Biochemical Mechanism of Cannabidiol in the Management of the Inflammatory and Oxidative Processes Associated with Endometriosis. Int J Mol Sci. 2022 May 12;23(10):5427. doi: 10.3390/ijms23105427. PMID: 35628240; PMCID: PMC9141153.

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