Save 27% on Your Shopping
May 13, 2021

CBD vs CBDa: Health Benefits, Side Effects, FAQ


As the popularity of CBD continues to increase worldwide, many people are doing their homework and researching the product and its benefits. They are also asking about the difference between CBD vs CBDa. Just a little research on the internet can quickly lead you into a minefield of information. Some of this is presented in layman’s terms, easy to understand and approachable. The other end of the spectrum is heavy on data and scientific terminology. Though the information is important, it can be difficult to decipher, and sometimes lead to confusion. 

So, in plain English, what is the distinction between CBD and CBDa

Today we’re breaking down some of those differences for you. We’re demystifying CBD and CBDa, answering the most frequently asked questions about the health benefits of these gifts from Mother Nature.


CBD and CBDa are both cannabinoids and are a type of natural compound found in cannabis plants. 

CBDa (or cannabidolic acid) is naturally found in cannabis plants such as hemp and marijuana. It is the most natural, potent, and rawest form of CBD, and is the acidic type of CBD that hasn’t been broken down through processing such as drying, curing, or heating (also known as decarboxylation). To preserve and gain the full benefits of CBDa, a cold extraction process should be used. 

Both CBDa and CBD derived from cannabis plants such as hemp and marijuana are “non-psychoactive compounds”... meaning they do not give you a sensation of feeling high or stoned. 

A comparison between CBD and CBDa can sometimes be difficult. The two compounds give distinct therapeutic advantages based upon their interactions with the various structures of the body. Research suggests CBDa is 1000 times more potent than CBD in certain ways. (1) This means CBDa has higher levels of bioactivity and bioavailability than CBD, so smaller doses can be used to give similar benefits. 

What Are The Health Benefits Of CBDa And CBD?

CBDa, in raw cannabis plants, exists in fairly large quantities and you can find it in products such as Nesas Organic Full Spectrum Hemp Oil. For example, hemp is rich in CBD and contains at least 10% more CBD than marijuana.

Cannabinoids are also found in the human body and are used by the endocrine system to support many different bodily functions such as: (2) 

  • Respiration
  • Metabolism
  • Reproduction
  • Sensory perception
  • Movement
  • Sexual development
  • Growth

For this reason, cannabinoids may be considered a health supplement as cannabis plants contain many dozens of cannabinoids. (3)  

CBDa Benefits

Research on CBDa is ongoing, with more information coming to light all the time. As we already understand it, some of CBDa’s many benefits may include:

  • Supporting a healthy cellular response: Some research concludes that CBDa may have a positive effect on the body’s response to cellular and tissue support. (4)  
  • Relief from nausea and vomiting: One study on rats and the Suncus murinus (Asian house shrew) revealed that CBDa may help to reduce nausea and vomiting by enhancing 5-HT1A receptor activation. (5)  
  • May reduce stress levels: A 2008 study showed that CBDa may help to reduce stress-induced behavior. (6)  
  • Ease joint discomfort: Although more research is needed, CBDa seems to support healthy joints by producing an anti-hyperalgesia effect in a rodent model. (7)  

CBD Benefits

Many of the benefits of CBDa are also present in CBD. And just as the research continues into CBDa, the same is true for CBD. Here are some of the known attributes of CBD:

  • Supports internal balance (homeostasis): Homeostatic imbalance occurs when cells in the body do not function properly, working together in harmony. Cellular disruption may result. CBD may help to support any internal imbalances. (8)   
  • Promotes relaxation and mood stabilization: Growing evidence suggests CBD encourages the body to relax, and thus may improve mood. (9)  
  • Helps with healthy skin, nails, and hair: There is some evidence to suggest CBD has the potential to support skin health and disorders. (10)   
  • May promote cardiovascular and circulatory system health: Studies conclude that CBD may have the ability to support healthy blood flow and reduce the effects of oxidative stress and cardiac dysfunction. (11, 12)  
  • Promotes better sleep patterns: Research shows that CBD can be effective in the promotion of sleep. (13)  

FAQs for CBDa and CBD

Is CBD safe? 

Although more research is needed, CBD is generally regarded as safe, as it is well tolerated by the body. Some side effects may occur such as dry mouth, diarrhea, reduced appetite, drowsiness, and fatigue. (14) 

Will CBDa or CBD get me high? 

No, CBDa and CBD will not get you high. It is non-intoxicating. Hemp contains very little THC (the main psychotropic compound in cannabis that produces the high sensation), under 0.3%.

How do I know which product is the best to buy? 

Look for high-quality products such as Nesas Beyond Organic CBDa Hemp Extract. This is a nutrient-rich, raw, and scientifically perfected product that works on the cellular level. 

It supports the body in many ways including reducing stress, improving focus and mood, promoting better sleep, enhancing joint and bone health, providing support for discomfort, and many more. By purchasing Nesas Hemp you can restore internal balance with just a few drops. 

How is CBD taken? 

CBD usually comes in tincture form and involves applying drops under the tongue and holding for a few moments before swallowing. Topical creams and ointments are also commonly available. 

Is Nesas Hemp Natural? 

Yes. Nesas Organic Full-Spectrum Hemp Extract is gluten-free, certified organic, non-GMO, pesticide-free, and vegan. It is made with Living Hemp - a rare form of hemp that is delicately produced by using the whole plant. The cold extraction method, unique to Nesas Hemp, sustains the plant’s natural molecular structure and contains vital nutrients, minerals, and vitamins.

What is the recommended serving size? 

Serving sizes can vary from person to person, however, 5-7 drops to up to one-half dropper twice per day is suggested.

Are CBDa and CBD legal? 

Yes. Both CBDa and CBD are legal in all 50 states of the U.S.

How does CBDa work? 

CBDa, like CBD, interacts with the endocannabinoid system within the body. It works with CB1 receptors in the brain and CB2 receptors throughout the body. As a result, it can offer benefits for the whole body to maintain a healthy equilibrium. (15)

While research into CBDa is still in the early stages, studies have shown great potential for its uses and health benefits. As more clinical trials are carried out, both CBDa and CBD will no doubt continue proving themselves as one of Mother Nature’s great healing gifts.


Buy a Nesa's Hemp CBDa
This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A doctor’s advice should be sought before using this and any supplemental dietary product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Void where prohibited by law.
usercrossmenu linkedin facebook pinterest youtube rss twitter instagram facebook-blank rss-blank linkedin-blank pinterest youtube twitter instagram