Entourage Effect - Biggest Influence is CBD
Cannabis plants contain more than 120 different Phyto-cannabinoids, terpenes, and other compounds. All of these compounds act on the endocannabinoid system (ECS) in our body which plays a significant role in regulating many functions including pain, stress, sleep, mood, memory, appetite, reproduction and fertility, metabolism, and immune function. ECS receptors are found everywhere throughout our bodies.
Two cannabinoids: Cannabidiol (CBD) and THC have received most of the attention from doctors, researchers, the public, and the media. They are also the two most researched cannabinoids in the cannabis plant. People know about them and consume both of them for different reasons and in different ways. A lot of people use only one cannabinoid at a time, either THC or CBD. For instance, CBD is available in isolate form and has had all other compounds removed.
Research shows that taking cannabinoids together with all of the other secondary compounds found in the cannabis plant, like terpenes and terpenoids, is much more effective than just taking CBD or THC alone. This phenomenon happens due to the interaction between cannabinoids and terpenes found in the plant. This interaction causes a stronger effect and is called “Entourage Effect”.
The phrase “Entourage Effect” was first used in the cannabis context in 1998 by a group of scientists including “the father of cannabis research” Israeli biochemist Dr. Raphael Mechoulam. A bit later in 2011 this phrase “Entourage Effect” was popularized by neurologist, psychopharmacology researcher, and former President of the International Cannabinoid Research Society - Dr. Ethan B. Russo in his famous 2011 paper, “Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects”.
In this study, Dr. Russo researched and investigated cannabinoid interaction with other compounds found in cannabis plants like terpenes and terpenoids. His study found that in the Entourage Effect “The biggest influence is CBD” especially that CBD contradicts and mitigates THC induces effects by blocking some cannabinoid receptors. Dr. Russo says in his article that cannabinoid-terpenoid interactions “could produce synergy with respect to the treatment of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer of fungal and bacterial infections.”
So, as explained, with hemp products there is much more involved than just CBD and THC. There are over 100 other cannabinoids along with terpenes and terpenoids. What gives cannabis its “character” are all the compounds found in the plant. These cannabinoids work in unison for the betterment of the whole, THC included.
If you are looking to experience the Entourage Effect, Nesa’s Hemp produces the most natural, organic, pure, and unharmed oil on the market. The way Nesa’s presses its hemp is gentle and ensures that the cannabinoids, terpenes, and terpenoids are not lost or damaged. Nesa’s believes that nature has the answer, and the most complete representation of the plant has to be presented in the bottle. Nesa’s provides “living hemp” in a bottle, so you can receive the full benefits and nutrition of the Hemp plant. We promise the best quality and amazing results!