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Updated on November 13, 2024

Best CBDA oil

Fact Checked

Key takeaways

  • CBDA oil is a natural extract derived from raw hemp plants
  • CBDA is non-psychoactive and interacts with receptors in the body related to inflammatory conditions and mood.
  • CBDA is 1,000 times more effective than CBD in binding to the serotonin receptor associated with nausea and unease.
  • CBDA exhibited 10 times the anti-seizure effectiveness of CBD.
  • A study in 2018 found that CBDA was 100 times more active than CBD in models of inflammatory pain.
  • CBDA exhibits a significantly higher bioavailability compared to CBD, with absorption rates estimated to be 5 to 11 times higher when taken orally.
  • Approximately 279 articles have been published on CBDA with about 150 discussing the therapeutic effect of the compound.
  • CBD has been reported from research to possess neuroprotective, antioxidant, analgesic, antiemetic and anti-inflammatory properties.

While the hemp market is saturated with oils that often overpromise and underdeliver, there is a growing need to diversify into minor but effective cannabinoids like CBDA. Initially, CBDA was thought to be unstable due to harsh extraction processes that converts it to CBD. However, innovative extraction methods such as those developed by Nesas Hemp have demonstrated how it can be preserved and utilized effectively. This article will explore key facts about CBDA oils, their unique advantages over CBD oils and how they can contribute to expanding the hemp industry.

What is CBDA oil?

CBDA oil is a natural extract derived from raw hemp plants, containing cannabidiolic acid (CBDA), a precursor to CBD. Unlike CBD, which is formed through heating (decarboxylation), CBDA is preserved in its original acidic form by using unique extraction methods that avoid heat. Known for its non-psychoactive properties, CBDA interacts with receptors in the body related to inflammatory conditions and mood, potentially offering wellness support without the “high” associated with THC. CBDA oil is often praised for its purity and bioavailability, making it an increasingly popular choice for those seeking a natural wellness supplement.

Why CBDA is better than CBD?

  • Effectiveness

Research increasingly suggests that CBDA may effectively support the body’s natural responses to irritation, mild discomfort, and unease. Its interaction with the COX-2 enzyme is thought to play a significant role in these benefits, while its unique engagement with serotonin receptors may promote emotional balance and alleviate mild nausea. A 2013 study from scientists at Guelph University in Canada highlighted that CBDA is 1,000 times more effective than CBD in binding to the serotonin receptor associated with nausea and unease. Furthermore, research published in 2018 demonstrated that CBDA exhibited 10 times the anti-seizure effectiveness of CBD. Another study from the same year found that CBDA was 100 times more active than CBD in models of inflammatory pain​.

  • Bioavailability

Bioavailability refers to the proportion of a substance that enters the bloodstream when introduced into the body and is available for use or storage. This measurement is crucial as it determines how quickly and efficiently a compound can exert its effects. Recent findings suggest that CBDA exhibits a significantly higher bioavailability compared to CBD, with absorption rates estimated to be 5 to 11 times higher when taken orally. This enhanced bioavailability may allow users to achieve therapeutic benefits with smaller doses of CBDA, as its molecular structure is thought to facilitate more efficient absorption. Consequently, CBDA can act more forcefully on various conditions, potentially offering longer-lasting support​

  • Preservation of Natural Compounds

Full-spectrum CBDA products maintain the original acidic cannabinoids found in raw hemp, preserving natural compounds like terpenes which may offer their own supportive properties. This preservation is key to achieving what is known as the entourage effect, where plant compounds may work together in harmony to offer enhanced wellness effects. Many terpenes preserved in CBDA oils offer additional benefits, such as antioxidant properties, making CBDA products a compelling option for those seeking a holistic approach to wellness.

  • No Additives or Harsh Chemical Conversions

Many CBDA extraction methods, such as cold-press or minimal heat techniques, avoid harsh chemicals, retaining the plant’s integrity. This gentle process can result in a cleaner product, free from synthetic additives or chemical solvents, aligning with the preferences of consumers seeking natural, minimally processed options. By eliminating unnecessary additives, CBDA oils offer transparency and support a demand for clean-label products that prioritize plant purity and avoid potential contaminants.

  • Natural vs. Synthetic

CBDA offers a more natural profile, often without the synthetic processing steps required for CBD. With fewer alterations, CBDA oils more closely reflect hemp’s original composition, appealing to individuals who prioritize natural wellness products. For those who prefer minimally processed options, CBDA is an attractive choice that aligns with a holistic, plant-based lifestyle, providing a cannabinoid in its original state as nature intended.

  • Fewer to No Side Effects

CBDA’s natural, minimally processed profile may result in fewer side effects compared to CBD, which undergoes decarboxylation and sometimes additional processing. With CBDA, users may experience supportive effects with lower dosages, potentially reducing the risk of side effects often seen with higher doses of other cannabinoids.

  • Greater Entourage Effect

Full-spectrum CBDA products retain cannabinoids, terpenes, and flavonoids in their natural state, offering a robust entourage effect. This synergy among plant compounds may amplify their overall wellness support, aligning with the holistic approach many consumers prefer. CBDA’s raw form includes a full spectrum of cannabinoids, unlike many processed CBD products, which supports a more balanced, complete option for physical and mental wellness through nature’s comprehensive profile.

Top Benefits of CBDA as reported from research

Research on cannabidiolic acid (CBDA) is rapidly expanding, with approximately 279 articles published in the PubMed Database. Notably, around 150 of these articles focus on the therapeutic benefits of CBDA. Below, we discuss some of the most frequently reported advantages associated with this compound.

  • Anti-inflammatory Properties

Information from a 2023 research paper published in the International Journal of Molecular Science, shows that CBDA has the ability to modulate inflammatory responses. It may help in reducing inflammation by interacting with the body's immune system.

  • Antiemetic Effects

Antiemetic effects refer to the ability of a substance to prevent or alleviate nausea and vomiting. These effects are crucial in various medical situations, such as post-operative recovery or during chemotherapy, where nausea can significantly impact a patient's comfort and quality of life. Research from a 2021 study published in Cannabis and Cannabinoid Research indicates that CBDA may help reduce feelings of nausea and promote overall comfort.

  • Antioxidant Activity


Findings from a 2021 study conducted at the Medical Academy, Lithuania shows CBDA has 3 times more antioxidant activity than CBD.  exhibits antioxidant properties, which may contribute to cellular health. Antioxidants play a crucial role in neutralizing free radicals, thus protecting cells from damage.

  • Anxiolytic Effects


A study published in the British Journal of Pharmacology in 2017 reveals that CBDA may help promote a sense of calm and relaxation. CBDA was found to produce anxiolytic effect in laboratory animals at a dose of 0.0001 mg·kg⁻¹

  • Neuroprotective Properties


Information from a 2023 research article published International Journal of Molecular Science  indicates that CBDA may support brain health by providing protective effects on neural cells.

  • Pain Management Support

A 2021 study published in Neuroscience found that CBDA may assist in promoting comfort and relaxation, contributing to overall well-being. This potential benefit makes it appealing for those seeking natural relief.

Why Nesas Hemp Oils Stands out among others

At Nesas Hemp, our oils are non-GMO and produced under stringent quality standards, ensuring they free from mold and other contaminants. We hold certifications that affirm our commitment to excellence, making our oils one of the best in the market.

Our unique cold pressed extraction methods preserve the natural properties of CBDA, resulting in high-quality oils that retain their effectiveness. By using cutting-edge techniques, we maximize the potency and purity of our products. Additionally, quality CBDA products undergo rigorous third-party lab testing to verify potency, purity, and the absence of contaminants. Our products are third-party tested by ACS Laboratory to ensure they meet the highest safety standards, remaining free from pesticides, heavy metals, and residual solvents. This testing is essential for validating cannabinoid content and purity, fostering trust with consumers who prioritize transparency and product quality.

Our commitment to quality and effectiveness is echoed by our customers. UFC Fighter Giga Chikadze shares his experience, stating, "This is the best CBD I’ve ever tried. Can’t go a day without it. It’s made a massive difference in my surgery recovery. Getting ready for the next fight."

How To Use CBDA For Best Results

  • Determine the Right Dosage

Start with a low dose of CBDA and gradually increase it based on your body's response. It's advisable to consult with a healthcare professional or a CBD expert to find the optimal dosage for your needs.

  • Choose the Right Product Form

CBDA is available in various forms, including oils, tinctures, capsules, and edibles. Select the form that best suits your lifestyle and preferences. Oils and tinctures allow for quick absorption, while capsules offer convenience.

  • Take It Consistently

For optimal results, incorporate CBDA into your daily routine. Consistency is key, as it may take time for the compound to build up in your system and provide its benefits.

  • Consider Timing

Depending on your goals, the timing of CBDA consumption may vary. For general wellness, taking it in the morning can be beneficial. If using it for relaxation or to support recovery, consider taking it in the evening.

  • Monitor Your Response

Pay attention to how your body reacts to CBDA over time. Keeping a journal can help track any changes in your well-being, allowing you to adjust your dosage or usage as needed.

  • Stay Hydrated

Drinking plenty of water while using CBDA can help support your body’s natural processes and enhance the overall effectiveness of the compound.

  • Consult with a Healthcare Professional

If you have underlying health conditions or are taking other medications, it’s crucial to consult with a healthcare professional before starting CBDA to ensure safety and efficacy.

Safety tips for using CBDA oils

While CBDA is generally well-tolerated, individual responses can vary. To help minimize potential side effects, here are a few safety tips to enhance your experience and promote safe use.

  • Consult a Healthcare Professional

Before starting CBDA oils, consult with a healthcare professional, especially if you have underlying health conditions or are taking other medications. This will reduce your chances of experiencing drug-drug interactions or allergies.

  • Start with a Low Dose

Begin with a low dose to assess how your body reacts. Gradually increase the dosage as needed while monitoring any effects.

  • Read Product Labels

Carefully read the labels for dosage instructions and ingredient information. Ensure the product is made from high-quality, non-GMO hemp and is free from additives.

  • Check for Third-Party Testing

Choose CBDA oils that have undergone third-party lab testing. This ensures the product is tested for potency, purity, and contaminants like pesticides or heavy metals.

  • Avoid Driving or Operating Heavy Machinery

If you're new to CBDA or if it causes drowsiness, avoid driving or operating heavy machinery until you know how it affects you.

  • Monitor for Side Effects

Be aware of potential side effects such as fatigue, changes in appetite, or digestive issues. If you experience adverse effects, discontinue use and consult a healthcare professional.

  • Store Properly

Keep CBDA oils in a cool, dark place to preserve their potency and prevent degradation. Ensure they are out of reach of children and pets.

  • Know Local Laws

Be informed about local regulations regarding the use of hemp products, including CBDA oils, as laws can vary by location.

  • Avoid Mixing with Alcohol or Other Substances

Mixing CBDA oils with alcohol or certain medications can enhance sedation or other effects. It’s best to avoid combining them until you understand how CBDA affects you.

Frequently Asked Questions

Is CBDA safe?

Yes, CBDA is generally considered safe for most individuals when used responsibly. Studies and anecdotal reports indicate that CBDA is well-tolerated, with only mild side effects like fatigue or changes in appetite occasionally reported. However, individual responses can vary, so it’s wise to consult a healthcare professional, especially if you have any medical conditions or are taking medications, as CBDA may interact with certain drugs. Choosing high-quality products that are third-party tested for purity, potency, and contaminants like pesticides or heavy metals is essential for safety. Starting with a low dose and gradually increasing it can also help minimize the risk of side effects, making CBDA a safe and effective choice for many as part of a balanced approach to wellness.

Can CBDA oil make you feel “high”?

No, CBDA oil will not make you feel “high.” Unlike THC, CBDA does not have psychoactive effects and does not interact with the brain’s receptors in the way that causes the euphoria or “high” associated with cannabis. CBDA primarily works on different receptors related to inflammation, serotonin, and other physiological processes, offering potential wellness benefits without altering perception or cognitive function. As a non-psychoactive compound, CBDA oil can be used safely for those who want the benefits of cannabinoids without the intoxicating effects.

What are the legal considerations for CBDA?

CBDA’s legality depends on its source and local laws. In the U.S., hemp-derived CBDA (under 0.3% THC) is federally legal, though state regulations vary. The FDA requires accurate labeling and prohibits unverified medical claims. Internationally, CBDA regulations differ, so travelers should check local laws before bringing products across borders. Many areas mandate third-party testing for purity and safety, ensuring regulatory compliance. Understanding these rules helps consumers make informed, legal choices when using CBDA.

Disclaimer
The content on Nesa's Hemp blog is for educational purposes only. We meticulously research and cite our sources, but advise consulting a professional before making decisions based on our information. We derive our content from reputable studies and publications, but individual circumstances may vary. We cannot guarantee the accuracy or applicability of our content to every situation. Nesa's Hemp blog and its authors are not liable for any loss or inconvenience resulting from reliance on our information. By using our blog, you waive any claims against us regarding the accuracy or completeness of our content.

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This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use if you have a serious medical condition or use prescription medications. A doctor’s advice should be sought before using this and any supplemental dietary product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. Void where prohibited by law.
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