Updated on January 31, 2024

CBD for gerd acid reflux

Fact Checked

Key takeaways

  • There is limited research describing the role of CBD in Gerd acid reflux.
  • A 2017 study shows that CBD may modulate the secretion of stomach acids which may be useful in improving the symptoms of Gerd Acid reflux.
  • CBD’s anti-inflammatory, analgesic and muscle relaxant effect may be effective at improving symptoms of gerd acid reflux.
  • It is not advisable to mix CBD and antacids as this may lead to several side effects like diarrhea.

CBD, may hold some potential therapeutic benefits for people battling with Gastroesophageal Reflux Disease (GERD) or acid reflux. While research is ongoing, CBD's anti-inflammatory and muscle-relaxant properties have led to interest in its potential to alleviate symptoms associated with acid reflux.

What is Gerd Acid reflux?

GERD stands for Gastroesophageal Reflux Disease. It is a chronic condition where stomach acid consistently flows back into the esophagus, causing irritation and inflammation. This backflow of stomach acid can lead to symptoms commonly known as acid reflux.

Symptoms of GERD include heartburn, regurgitation, chest pain, difficulty swallowing, and a persistent cough. If left untreated, GERD can result in complications such as esophagitis, Barrett's esophagus, and an increased risk of esophageal cancer. Lifestyle modifications, medications, and, in severe cases, surgery, are often used to manage GERD and alleviate symptoms.

What does Research say about CBD for Gerd Acid reflux?

There is limited scientific evidence regarding the specific efficacy of CBD in treating Gastroesophageal Reflux Disease (GERD) or acid reflux. A 2017 review notes that a person's endocannabinoid system, responsive to CBD, exhibits antisecretory effects on gastric acid and possesses anti-inflammatory properties within the digestive system, suggesting a potential relief for GERD symptoms.

CBD interacts with the endocannabinoid system, a regulator of various physiological functions, including those in the gastrointestinal system. With its anti-inflammatory and muscle-relaxant properties, CBD theoretically has the potential to alleviate symptoms associated with GERD. Nevertheless, individual responses to CBD can vary, and its effects on acid reflux may not be universally consistent.

CBD interacts with a person's cannabinoid receptors, particularly in the gastrointestinal tract. One potential impact of CBD is its ability to soothe soft muscle tissue, regulating muscle contractions and offering relief from heartburn discomfort.

How may CBD assist people with Gerd Acid Reflux?

While research on CBD's specific effects on acid reflux is ongoing, some potential ways in which CBD may influence the gastrointestinal tract that could potentially help reduce acid reflux include:

  1. Anti-Inflammatory Properties: CBD has been studied for its anti-inflammatory effects, which might help reduce inflammation in the digestive tract and alleviate symptoms associated with acid reflux.
  2. Muscle Relaxation: CBD is known for its muscle-relaxant properties. This could potentially help relax the muscles in the esophagus and prevent spasms or excessive contractions that contribute to acid reflux.
  3. Regulation of Gastrointestinal Contractions: CBD interacts with the endocannabinoid system, which plays a role in regulating muscle contractions in the gastrointestinal tract. This interaction may contribute to a more balanced and coordinated movement of muscles, potentially reducing the likelihood of acid reflux.
  4. Pain Relief: CBD's potential analgesic (pain-relieving) properties could help alleviate discomfort associated with acid reflux.
  5. Regulation of Acid Secretion: Some studies suggest that CBD may have an impact on gastric acid secretion, potentially helping to reduce excess acid production in the stomach.

Frequently asked questions

Can I take CBD with antacids?

No! Combining CBD with stimulants like Adderall may reduce appetite, while its interaction with diabetes medication metformin or certain heartburn drugs like Prilosec could elevate the risk of diarrhea.

Does CBD lower stomach acid?

Yes, cannabinoids like CBD have been found to suppress gastric acid secretion. The inhibitory impact of Cannabis or cannabinoid agonists on stomach acid secretion is likely linked to CB1 receptors. This inhibitory effect may be attributed to the activation of CB1 receptors situated on the vagal efferent pathways.

Can I take CBD with omeprazole?

No, CBD may influence the metabolism of omeprazole and risperidone through interactions with CYP2D6 enzymes.

Want to Learn More?

  1. Hemp History Timeline (CBD History)
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  3. What Is Ayurveda, And Is It For Me?
  4. Why Flavored CBD Is Low Quality
  5. How Heavy Metals And Pesticides Are Getting Into CBD Oil


Abdel-Salam, O. (2016). Gastric acid inhibitory and gastric protective effects of Cannabis and cannabinoids. Asian Pacific Journal of Tropical Medicine, 9(5), 413-419. https://doi.org/10.1016/j.apjtm.2016.04.021

Balachandran, P., Elsohly, M., & Hill, K. P. (2021). Cannabidiol Interactions with Medications, Illicit Substances, and Alcohol: A Comprehensive Review. Journal of General Internal Medicine, 36(7), 2074-2084. https://doi.org/10.1007/s11606-020-06504-8

Gotfried, J., Kataria, R., & Schey, R. (2017). Review: The Role of Cannabinoids on Esophageal Function—What We Know Thus Far. Cannabis and Cannabinoid Research, 2(1), 252-258. https://doi.org/10.1089/can.2017.0031

Adenusi, A. O., Magacha, H. M., Nwaneki, C. M., Asifat, O. A., & Annor, E. N. (2023). Cannabis Use and Associated Gastrointestinal Disorders: A Literature Review. Cureus, 15(7). https://doi.org/10.7759/cureus.41825

The content on Nesa's Hemp blog is for educational purposes only. We meticulously research and cite our sources, but advise consulting a professional before making decisions based on our information. We derive our content from reputable studies and publications, but individual circumstances may vary. We cannot guarantee the accuracy or applicability of our content to every situation. Nesa's Hemp blog and its authors are not liable for any loss or inconvenience resulting from reliance on our information. By using our blog, you waive any claims against us regarding the accuracy or completeness of our content.

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