The activity and interaction of CBD with receptors show promise in enhancing coordination and addressing symptoms associated with tremors. This article delves into the potential therapeutic benefits of CBD for tremors and how individuals may find relief.

Overview of tremors

Tremors are involuntary and rhythmic movements or shaking of a part of the body. They can affect various areas, such as the hands, arms, head, face, vocal cords, trunk, or legs. Tremors can be caused by various conditions, including neurological disorders, certain medications, or physiological factors. They are often noticeable when a person is trying to perform a voluntary movement, and the intensity can range from mild to severe. Treatment depends on the underlying cause, and in some cases, lifestyle changes or medications may help manage tremors.

Statistics indicate that approximately 10 million Americans are affected by Essential Tremors. This condition can impact daily activities, and while it is not life-threatening, it can significantly affect a person's quality of life.

Symptoms of tremors

Common symptoms of tremors include but are not limited to the following;

1. Rhythmic shaking of the hands, arms, head, legs, or torso.
2. Shaky voice.
3. Difficulty with writing or drawing.
4. Problems holding and controlling utensils, tools, or other items.

How may CBD assist people with tremors?

While research on CBD and tremors is ongoing, some studies suggest that CBD may have potential therapeutic effects for individuals experiencing tremors. Here are ways CBD may assist people with tremors:

1. Neuroprotective Properties: CBD's neuroprotective properties may help protect and support the health of neurons, potentially mitigating the progression of conditions that cause tremors.
2. Anti-Inflammatory Effects: CBD has anti-inflammatory properties that might be beneficial, especially if inflammation contributes to neurological disorders associated with tremors.
3. Calming Effects: CBD's anxiolytic (anxiety-reducing) properties may help alleviate stress and anxiety, which are known to make tremors worse. This calming effect could potentially reduce the intensity and frequency of tremors.
4. Modulation of Neural Signaling: CBD interacts with receptors in the endocannabinoid system, which plays a role in regulating various physiological functions, including those related to movement and coordination.
5. Improved Sleep: CBD may help individuals with tremors by promoting better sleep, as lack of sleep can worsen symptoms of tremors.

What research say about CBD and tremors?

CBD plays a role as a modulator of CB1 receptors, and research suggests a potential connection between CB1 agonists and the reduction of tremors in experimental models. CB1 receptors are part of the endocannabinoid system, a complex signaling network in the body. Activation of CB1 receptors by cannabinoids, such as CBD, influences various physiological processes, including those related to movement and coordination. Experimental studies have explored the impact of CB1 agonists, substances that activate these receptors, in mitigating tremors. The modulation of CB1 receptors by CBD may contribute to its potential therapeutic effects in managing conditions characterized by involuntary shaking or tremors.

Another research shows that the acute administration of CBD at a dose of 300 mg demonstrated a reduction in anxiety among patients with Parkinson's disease (PD). Furthermore, the study reported a decrease in tremor amplitude, suggesting a potential dual benefit of CBD in addressing both anxiety and tremors in individuals with PD.

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Sources

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Santos de Alencar S, Crippa JAS, Brito MCM, Pimentel ÂV, Cecilio Hallak JE, Tumas V. A single oral dose of cannabidiol did not reduce upper limb tremor in patients with essential tremor. Parkinsonism Relat Disord. 2021 Feb;83:37-40. doi: 10.1016/j.parkreldis.2021.01.001. Epub 2021 Jan 12. PMID: 33465546.

Arjmand, S., Vaziri, Z., Behzadi, M., Abbassian, H., Stephens, G. J., & Shabani, M. (2015). Cannabinoids and Tremor Induced by Motor-related Disorders: Friend or Foe? Neurotherapeutics, 12(4), 778-787. https://doi.org/10.1007/s13311-015-0367-5

Fabrício, M., Tumas, V., Castro, P. C., Ponti, M. A., Hallak, J. E., Zuardi, A. W., S Crippa, J. A., & Nisihara Chagas, M. H. (2020). Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson’s disease. Journal of Psychopharmacology. https://doi.org/10.1177/0269881119895536

Sousa A, DiFrancisco-Donoghue J (July 24, 2023) Cannabidiol and Tetrahydrocannabinol Use in Parkinson’s Disease: An Observational Pilot Study. Cureus 15(7): e42391. doi:10.7759/cureus.42391