Key takeaways
- CBG is the precursor to THC, CBD, and other cannabinoids, synthesized from cannabigerolic acid (CBGA).
- Found in minimal amounts in cannabis, typically less than 1%, making it a minor cannabinoid.
- Research suggests CBG may have anti-inflammatory, neuroprotective, antioxidant, antibacterial, and appetite-stimulating effects.
- CBG shows promise in reducing inflammation associated with conditions like IBD, arthritis, and neuroinflammatory disorders.
- Studies indicate CBG may protect against neurodegenerative diseases like Huntington's, Parkinson's, and Alzheimer's.
- Unlike THC, CBG does not produce a "high," making it suitable for therapeutic use without intoxicating effects.
- In some cases, body weight may play a role in determining the appropriate CBG dosage, with higher doses potentially needed for individuals with higher body weights.
- The method of administration can affect how CBG is absorbed and metabolized by the body, influencing the dosage needed to achieve the desired effects.
It is impossible to discuss cannabinoids without making reference to CBG. CBG is known as the stem cell of cannabinoids and it plays a major role in the synthesis of other cannabinoids. Like CBD and THC, CBG possess some excellent therapeutic benefits which can only be enjoyed with the appropriate dosage. In this article, we would look at the factors to consider when choosing CBG dosage and more.
What is CBG?
Cannabigerol (CBG) is one of the many cannabinoids found in the cannabis plant even though it is typically present in lower concentrations compared to other cannabinoids like THC and CBD. It is often referred to as the "stem cell" or "mother" cannabinoid because it is the precursor to other cannabinoids. CBG is produced from cannabigerolic acid (CBGA), which is converted into various cannabinoids through enzymatic processes as the cannabis plant matures.
CBG has garnered attention for its potential therapeutic properties, although research on its effects is still in the early stages. Some studies suggest that CBG may have anti-inflammatory, neuroprotective, and analgesic properties, making it potentially useful for conditions such as inflammation, pain, and neurodegenerative diseases.
Like other cannabinoids, CBG interacts with the body's endocannabinoid system, influencing various physiological processes such as mood, appetite, pain sensation, and immune function. Unlike THC and some of its sister molecules, CBG is non-psychoactive and does not make users high.
How to dose your CBG products
Dosing CBG products can vary depending on factors such as individual tolerance, the concentration of CBG in the product, and the desired effects. Here are some general guidelines for dosing CBG products:
- Start Low and Go Slow: If you're new to using CBG products, start with a low dose and gradually increase it over time as needed. This allows you to assess your tolerance and adjust the dose accordingly.
- Read the Label: Pay attention to the concentration of CBG in the product and follow the recommended dosage instructions provided by the manufacturer. CBG products come in various forms, including oils, capsules, edibles, and topicals, each with its own recommended dosing guidelines.
- Consult with a Healthcare Professional: If you're unsure about the appropriate dose for your specific needs or if you have any underlying health conditions, consult with a healthcare professional before using CBG products. They can provide personalized guidance based on your individual circumstances.
- Consider Your Goals: Consider what you're using the CBG product for and adjust the dose accordingly. For example, lower doses may be suitable for general wellness or mild symptoms, while higher doses may be necessary for managing more severe symptoms or conditions.
- Be Patient: It may take some time to find the optimal dose that works best for you. Be patient and give your body time to adjust to the effects of CBG. Keep track of your dosage and any effects you experience to help fine-tune your dosing regimen.
- Monitor for Side Effects: Pay attention to how your body responds to the CBG product and watch for any potential side effects. If you experience any adverse reactions, such as dizziness, nausea, or changes in mood, consider lowering the dose or discontinuing use.
Factors that determine CBG Dosage
Several factors can influence the appropriate CBG dosage for an individual. These factors include:
- Body Weight: Generally, individuals with higher body weights may require higher doses of CBG to achieve the desired effects compared to those with lower body weights.
- Metabolism: The rate at which your body metabolizes CBG can vary from person to person. Individuals with faster metabolisms may process CBG more quickly, potentially requiring higher doses to maintain the desired effects.
- Tolerance: Your tolerance to CBG can develop over time with regular use. Individuals with higher tolerance levels may require higher doses to achieve the same effects as those with lower tolerance levels.
- Individual Sensitivity: Each person's endocannabinoid system responds differently to cannabinoids like CBG. Some individuals may be more sensitive to CBG and require lower doses to achieve the desired effects, while others may need higher doses.
- Medical Conditions: The specific medical condition being treated can influence the optimal CBG dosage. Individuals with more severe symptoms or conditions may require higher doses for symptom relief.
- Desired Effects: The desired effects of CBG can vary widely among individuals. Some may be using CBG for general wellness purposes, while others may be seeking symptom relief for specific conditions. The desired effects will influence the appropriate dosage.
- Product Potency: The potency of the CBG product you're using will also affect the dosage. Higher potency products will require smaller doses to achieve the same effects as lower potency products.
- Method of Administration: The method of administration can impact how quickly and efficiently CBG is absorbed into the body. For example, sublingual tinctures may have faster onset times compared to oral capsules or edibles.
- Previous Experience: Your previous experience with CBG or other cannabinoids can also inform your dosage decisions. If you've used CBG or similar products before, you may have a better understanding of your tolerance and how your body responds to different doses.
Frequently asked questions
What is the typical range of CBG dosages?
CBG dosages can range from as low as 5-10 milligrams to over 100 milligrams per dose, depending on factors such as product potency and individual needs.
How often should I take CBG?
The frequency of CBG dosing can vary depending on individual needs and the duration of the effects. Some people may take CBG once or twice daily for ongoing symptom relief, while others may use it as needed.
Should I take CBG with food or on an empty stomach?
Whether to take CBG with food or on an empty stomach depends on personal preference and the method of administration. Some people may find that taking CBG with food helps minimize potential digestive discomfort.
Can I overdose on CBG?
There is no known lethal dose of CBG, and overdosing is rare. However, taking excessively high doses of CBG may lead to adverse effects such as drowsiness, dry mouth, or gastrointestinal discomfort.
How long does it take to feel the effects of CBG?
The onset of CBG effects can vary depending on factors such as the method of administration and individual metabolism. Sublingual administration typically has a faster onset compared to oral ingestion.
Can I combine CBG with other medications or supplements?
CBG may interact with certain medications or supplements, so it's essential to consult with a healthcare professional before combining CBG with other substances.
Sources
Calapai, F., Cardia, L., Esposito, E., Ammendolia, I., Mondello, C., Giudice, R. L., Gangemi, S., Calapai, G., & Mannucci, C. (2022). Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives. Evidence-Based Complementary and Alternative Medicine : ECAM, 2022. https://doi.org/10.1155/2022/3336516
Vernail, V. L., Bingaman, S. S., Silberman, Y., Raup-Konsavage, W. M., Vrana, K. E., & Arnold, A. C. (2022). Acute Cannabigerol Administration Lowers Blood Pressure in Mice. Frontiers in Physiology, 13. https://doi.org/10.3389/fphys.2022.871962
Amstutz, K., Schwark, W. S., Zakharov, A., Gomez, B., Lyubimov, A., Ellis, K., Venator, K. P., & Wakshlag, J. J. (2022). Single dose and chronic oral administration of cannabigerol and cannabigerolic acid-rich hemp extract in fed and fasted dogs: Physiological effect and pharmacokinetic evaluation. Journal of Veterinary Pharmacology and Therapeutics, 45(3), 245-254. https://doi.org/10.1111/jvp.13048
