Updated on March 12, 2024

CBD Side Effect

Fact Checked

Key takeaways

  • CBD can produce side effects in some individuals due to its interaction with the ECS receptors and other receptors in the body.
  • The side effects of CBD may vary from person to person and may be influenced by dosage, presence of other medications, quality of CBD products and ingredients in the CBD products.
  • Common CBD side effects include dry mouth, change in appetite, and diarrhea.
  • High quality products from reputable companies are less likely to contain contaminants which may increase the chances of a side effect.
  • Taking CBD everyday may play important roles in promoting good health.

While the WHO has attested to the safety of CBD, individuals may experience certain side effects, typically of a mild nature. In this article, we will explore the potential side effects of CBD and discuss ways to minimize them.

Does CBD produce side effects?

Yes, CBD can produce side effects in some individuals due to its interactions with the endocannabinoid system (ECS) and other receptors in the body. The ECS plays a crucial role in regulating various physiological functions, including mood, sleep, appetite, and immune response.

Factors influencing CBD’s side effects?

  1. Individual Variation: People's bodies react differently to substances, and what works well for one person may cause side effects in another. Individual factors such as metabolism, genetics, and overall health can influence how the body responds to CBD.
  2. Dosage: The dosage of CBD can impact the likelihood and severity of side effects. Higher doses may increase the risk of adverse reactions, and individuals may respond differently to varying concentrations of CBD.
  3. Interaction with Medications: CBD can interact with certain medications, affecting their metabolism and potentially causing side effects. You can read our article on possible drugs that should not be combined with CBD.
  4. Quality of CBD Products: The purity and quality of CBD products can vary. Contaminants or impurities in poorly manufactured CBD products may contribute to adverse effects.
  5. Formulation and Ingredients: CBD products may contain other ingredients, such as carrier oils or additives, that can contribute to side effects. Individuals may be sensitive or allergic to specific components of the product.

Common CBD Side effects

While CBD is generally well-tolerated by many people, it can cause side effects in some individuals. It's important to note that the side effects are typically mild, and not everyone experiences them. Common side effects of CBD may include:

  1. Dry Mouth: CBD can reduce saliva production, leading to a dry or cottonmouth sensation.
  2. Changes in Appetite: Some people may experience changes in appetite, either an increase or decrease.
  3. Fatigue: CBD can cause feelings of drowsiness or tiredness, especially at higher doses.
  4. Diarrhea: In some cases, CBD may cause digestive issues such as diarrhea.
  5. Interactions with Medications: CBD can interact with certain medications, so it's crucial to consult with a healthcare professional, especially if you are taking other medications.

How to minimize CBD's Side effect

Consider the following tips if you want to minimize the potential side effects of CBD;

  1. Start with a Low Dose: Begin with a low dose of CBD and gradually increase it if needed. This allows your body to acclimate to the compound, reducing the likelihood of side effects.
  2. Choose High-Quality Products: Opt for reputable CBD products from trusted manufacturers. High-quality products undergo rigorous testing for purity and potency, minimizing the risk of contaminants.
  3. Select the Right Delivery Method: CBD is available in various forms, including oils, capsules, edibles, and topicals. Experiment with different delivery methods to find the one that suits you best and minimizes side effects.
  4. Monitor Your Body's Response: Pay attention to how your body reacts to CBD. If you notice any adverse effects, consider adjusting the dosage or discontinuing use. Keeping a journal can help track changes and identify patterns.
  5. Check for Additives: Read the product's ingredient list to ensure there are no additives or components that may trigger adverse reactions. Choose CBD products with minimal additional ingredients.
  6. Understand Your Sensitivity: Individuals have varying levels of sensitivity to substances. Be aware of your own sensitivity and listen to your body's signals. If you're particularly sensitive, even low doses of CBD may be effective.
  7. Consider Full-Spectrum vs. Isolate: Full-spectrum CBD products contain a range of cannabinoids, while CBD isolate contains only pure CBD. Some individuals find that the additional cannabinoids in full-spectrum products provide a more balanced effect, potentially minimizing side effects.
  8. Stay Hydrated: CBD may cause dry mouth as a side effect. Staying hydrated can help alleviate this symptom.
  9. Take With Food: Consuming CBD with food may help reduce the risk of digestive issues. Consider taking CBD oil or edibles during or after meals.

Frequently asked questions

Is it okay to consume CBD everyday?

Yes, consistency is the key to enjoying the maximum benefits of CBD. Like diet and exercise, adding CBD to your routines may play important roles in promoting good health.

Are side effects more likely with higher doses of CBD?

Yes, higher doses of CBD may increase the likelihood and severity of side effects. It's advisable to start with a low dose and gradually increase it if needed.

What should I do if I experience side effects from CBD?

If you experience side effects, consider adjusting the dosage or discontinuing use. It's important to listen to your body's signals and consult with a healthcare professional if the side effects persist or are severe.

Are all CBD products the same regarding side effects?

No, the quality and composition of CBD products can vary. High-quality products from reputable manufacturers are less likely to contain contaminants or additives that may contribute to side effects. Always choose products carefully and read ingredient lists.

Want to Learn More?

  1. Healing Herbs and Holistic Ingredients: Hemp Oil Recipes for a Sustainable Kitchen
  2. Green Beauty — Making DIY Skincare with Organic Hemp Skincare
  3. CBDa, CBD, THC, and Drug Tests: What You Need to Know
  4. What are Cannabinoids?
  5. Benefits of CBD Oil for Athletes


  1. Huestis, M. A., Solimini, R., Pichini, S., Pacifici, R., Carlier, J., & Busardò, F. P. (2019). Cannabidiol Adverse Effects and Toxicity. Current Neuropharmacology, 17(10), 974-989. https://doi.org/10.2174/1570159X17666190603171901
  2. Iffland, K., & Grotenhermen, F. (2017). An Update on Safety and Side Effects of Cannabidiol: A Review of Clinical Data and Relevant Animal Studies. Cannabis and Cannabinoid Research, 2(1), 139-154. https://doi.org/10.1089/can.2016.0034
  3. Pauli, C. S., Conroy, M., Vanden Heuvel, B. D., & Park, S. (2020). Cannabidiol Drugs Clinical Trial Outcomes and Adverse Effects. Frontiers in Pharmacology, 11, 505190. https://doi.org/10.3389/fphar.2020.00063
  4. Moltke, J., Hindocha, C. Reasons for cannabidiol use: a cross-sectional study of CBD users, focusing on self-perceived stress, anxiety, and sleep problems. J Cannabis Res 3, 5 (2021). https://doi.org/10.1186/s42238-021-00061-5
  5. Brown, J. D., & Winterstein, A. G. (2019). Potential Adverse Drug Events and Drug–Drug Interactions with Medical and Consumer Cannabidiol (CBD) Use. Journal of Clinical Medicine, 8(7), 989. https://doi.org/10.3390/jcm8070989
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